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Emerging Oncology Trends: 2021 and Beyond

2020 was an unforgettable year. COVID-19 sent shock waves across the globe, claiming more than 1.5 million lives with the end not yet in sight. In the wake of this tragedy, the pharmaceutical market raced to develop treatments. New vaccines for coronavirus have emerged in record time. In many ways, 2020 was a year of medical triumphs, but the fallout from the pandemic will linger for years.

As the world enters 2021, cancer patients face unique struggles. The global pandemic has had a significant impact on oncology care and clinician access for patients. However, newly approved therapies offer extra weapons in the fight against cancer and as we step into a new year, there is a lot to be encouraged about.

COVID-19, Cancer Care, and the Rise of Telemedicine
In 2020, oncology centers helped lead the shift toward telemedicine. Many providers urged cancer patients to seek care through virtual platforms. Thousands of medical organizations began to offer a wide range of telehealth services. Payors have been paying close attention to these trends and are re-evaluating reimbursement policies with regard to virtual care.

Telehealth appears to offer a significant reduction in costs for some patient groups. Historically, many cancer patients preferred to seek in-person care. The evidence is mounting that telehealth provides faster, less expensive care. Increased use of telehealth may shrink ballooning cancer care costs. Telehealth could also help immunocompromised patients avoid deadly infections.

The increase in telehealth coincides with a rise in wearable devices, apps, and other digital tools. The pandemic has sparked greater public health consciousness and patients are now eager to monitor their health more closely on their own. Many cancer patients are older and they may be less tech-savvy, but they are willing to use these new tools to help protect their well-being.

Providers can leverage wearable devices and remote digital tools to gain a clearer picture of patients’ health. Digital tools may eliminate the need for face-to-face contact, providing cancer care to patients at home. Payors are also enthusiastic about tools that help prevent costly health complications. When combined with telehealth, digital tools offer clear health benefits. Evidence is mounting that these tools may reduce healthcare costs. As a result, they’re likely to lead to long-term changes in cancer care.

Therapeutic Trends
Precision medicine is on the rise globally, with explosive growth in the field of oncology. A recent McKinsey & Company report states that “Oncology is at the vanguard of precision medicine.” In 2020, the industry continued to explore methods of personalizing cancer care. Chemotherapy could become increasingly obsolete as immunotherapy takes center stage. Diagnostic testing to identify the best therapeutic approaches on an individualized basis has become standard of care in many malignancies.

Researchers continue to develop new methods of targeting cancer cells. Healthcare providers are increasingly turning to germline and somatic testing in the clinic to help guide informed treatment decisions. Providers are refining treatment approaches and providing truly customized care. Demand for genetic testing is only expected to grow throughout 2021. Immunotherapy and pharmacogenomics are trending to dominate the market at some point in the near future.

Companies and Competitors
The oncology market remains competitive. Throughout 2020, companies aimed to control costs and shrink drug development timelines. Pharma companies raced to debut new treatments and streamline the development process. The competition will remain fierce throughout the coming year.

Even so, the global pandemic has helped spark interest in partnerships. Many organizations and companies collaborated to develop COVID-19 treatments and vaccines. Successful outcomes proved that collaborations could offer a win-win scenario. Companies that work together can secure an edge in the marketplace.

Governments and citizens like to see private companies working together for the public good. As the demand and costs for oncology treatments rise, new partnerships may prove a viable business strategy.

Industry Spending and Financial Outlook
The oncology market continues to expand at a rapid pace. Experts expect ongoing increases in cancer diagnoses over the next 10 years. Most of these increases will result from an aging population. By 2030, more than 70% of cancer diagnoses will occur among adults over 65. As millions of patients reach that threshold, cancer costs will continue to skyrocket.

Oncology will continue to dominate the healthcare sphere, securing the largest share of healthcare spending. Oncology costs will rise by 9%–12% annually through 2023, with global oncology costs exceeding $240 billion.

Payors and patients alike are anxious to control costs. Finding sustainable, cost-efficient treatments will be a priority. Even as new and better therapeutic approaches emerge, pharma companies can expect to face mounting pressure to reduce treatment costs.

Innovative and Emerging Treatments
Programmed cell death protein 1 (PD-1) and PD-1 ligand 1 (PD-L1) inhibitors continue to dominate the oncology market. Ongoing research suggests that patients treated with PD-1 and PD-L1 inhibitors experience significantly better outcomes across a variety of tumor types and hematologic malignancies. Demand is likely to increase throughout 2021.

Antibody-drug conjugates and Bruton tyrosine kinase inhibitors have also taken center stage. These drugs help shrink tumors while sparing healthy cells. Research has demonstrated that these treatments offer exceptional clinical efficacy and safety.

Throughout 2020, powerhouse drugs like Revlimid®, Keytruda®, and Imbruvica® continued to rake in billions in sales. In 2019, Revlimid, Keytruda, Opdivo®, Avastin®, and Imbruvica netted over $43 billion in combined sales. While new treatments continue to gain popularity, established drugs still claim a large market share.

The Year Ahead
By 2022, the top 15 cancer drugs are expected to generate almost $90 billion in sales annually. However, emerging treatments may shift the tide and open new pathways. 2020 demonstrated that the pharma market can produce effective treatments at an astonishing speed. 2021 is bound to be a year of even greater innovation and discovery in the field of oncology.

Therapeutic Area

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Matthew Gordon

VP, Real-World Evidence
Matthew has more than 25 years of experience in real-world evidence and observational, non-interventional research. He has led studies across the full life cycle—from startup through publication—supporting objectives that range from understanding a disease’s natural history to fulfilling global safety surveillance requirements. Matthew brings deep expertise in orphan disease programs, having overseen more than 25 long-term, global initiatives, as well as in disease and product registries, prospective pharmacoeconomic studies, and systematic literature reviews. Matthew leads the RWE Registries team, responsible for building the business and team. Prior to joining Aptitude Health, he held senior leadership roles at Parexel, Worldwide Clinical Trials, inVentiv Health Clinical, Quintiles Outcome, and ICON Clinical Research. Matthew holds a BA in sociology from Boston University, is a long-standing member of the International Society for Pharmacoeconomics and Outcomes Research (ISPOR), and is a frequent speaker at ISPOR, the Center for Business Intelligence, and related industry conferences.

Gerald Stanvitch, PhD

VP, Scientific Content

Cate Browning, PhD

VP, Global Medical Affairs

Erin Zingales Rau

VP, Account Services

Kelly Kocor

VP, People & Culture
Kelly leads both the human resources and talent acquisition teams, ensuring that Aptitude Health attracts, retains, and develops top personnel to drive our continued success. With over 17 years of experience transforming global HR initiatives, Kelly is an expert in harmonizing HR policies and fostering a culture of engagement and partnership. She is committed to partnering with all areas of the business to ensure full regulatory compliance and delivering value-added services to our organization and its people. Kelly is passionate about developing and implementing HR strategies that help support our employees’ professional and personal growth. She is dedicated to fostering a culture that encourages innovation, collaboration, and inclusivity, helping Aptitude Health continue to be a great place to work.

Bart Zygmond

VP, Finance
Bart brings a wealth of experience to the organization, having worked in the life sciences, pharmaceuticals, manufacturing, and service industries. With his expertise in financial reporting, US GAAP, SOX, cash flow modeling, and financial analysis, he plays a crucial role in the company’s financial management and strategy. Prior to joining Aptitude Health as VP, Finance, Bart held several controller positions: at Q2 Solutions, he oversaw the global finance team and financial operations, ensuring the accurate and timely financial reporting of the company. He also held controller positions at Domtar Inc and Veristat.

Eugene Vissers, MD

Senior VP, Global Scientific Content
Eugene is a seasoned medical doctor with over 20 years of international experience in pharma, consultancy, and agency environments. Eugene leads the US team of dedicated experts responsible for developing high-quality medical content. Prior to joining Aptitude Health, Eugene served as medical director at Ipsen and AstraZeneca. With both his medical degree and an MBA, Eugene brings a unique perspective to his role. His clinical background, combined with his business acumen, allows him to develop innovative strategies that drive results. Under Eugene’s leadership, the medical content team delivers scientific information of the highest quality, providing valuable insights to our clients around the world.

Adrian Barfield

VP, US Business Development

Kelley Hernandez

Executive VP, US Business Development
Kelley has over 18 years of experience in the oncology space. Kelley joined Aptitude Health after working with Cardinal Health, where she was part of the Healthcare and Analytics Division, and finished her tenure there with VitalSource™ (GPO division). As the leader of the strategic business development team for the US, Kelley brings a wealth of expertise to the organization. Her experience in the healthcare industry, combined with her ability to identify and capitalize on new business opportunities, is invaluable in driving the company’s growth and success. Kelley’s dedication to building strong relationships with life science partners is a testament to her commitment to delivering exceptional value to the healthcare industry.

Adam Sinensky, MBA

Chief Technology Officer

Adam has over 20 years of experience in the healthcare industry and an MBA in healthcare management. After 10 years as a strategy consultant to life science companies, Adam has spent the last decade as a product and strategy leader focused on bringing technology products to market across the payor, provider, and life sciences segments. By combining his business acumen and experience working directly with software developers, engineers, and data scientists, Adam has successfully led numerous product launches and enhancements from ideation to development and go-to-market initiatives. His product and change management expertise has led organizational shifts from services to technology at companies such as Change Healthcare and Datavant/Ciox. At Aptitude Health, Adam is responsible for growing our portfolio of product offerings by leveraging real-world data and artificial intelligence with our existing solutions and industry-leading Axess Network of healthcare providers. He also oversees our IT and cybersecurity teams.

Stefanie Daniels

Chief Commercial Officer

Stefanie is a seasoned healthcare executive with over 20 years of experience in oncology. She brings a wealth of knowledge and expertise to the organization. Stefanie joined Aptitude Health after spending over a decade as a senior director at Physicians’ Education Resource, an oncology CME vendor. During her tenure, she led and managed teams responsible for grant development/acquisition, program creation/execution, and faculty management. Stefanie’s deep understanding of the oncology industry and her ability to lead teams through complex projects make her a vital part of the organization’s success. Her dedication to providing high-quality solutions to our life science partners is a testament to her commitment to improving cancer patient care.

Jason Cash

Chief Financial Officer

Jason is an accomplished finance professional with over 20 years of experience in the pharmaceutical services industry. Throughout his career, he has demonstrated a keen ability to navigate high-growth organizations, delivering exceptional results. Before joining Aptitude Health, Jason served as the CFO of Veristat International, a global contract research organization. In this role, he led the financial strategy and played a pivotal role in driving the company’s growth and success. Jason’s wealth of experience and expertise in financial management make him an essential member of the leadership team. His strategic thinking and ability to drive results are highly respected within the industry.

Jez Moulding

Chief Executive Officer
Jez is a seasoned leader with over 20 years of experience in general management and regional president roles. He has a proven track record of success in the healthcare industry, having worked in the US, Japan, Australia, Korea, South Africa, France, and the UK for Sanofi, where he supported the launch of 10 new drugs across various therapeutic areas. As chief commercial officer at UDG Healthcare and EVP at Ashfield, Jez demonstrated his expertise in developing and implementing successful business strategies. He joined Aptitude Health from Pharmaspectra, an IQVIA business, where he served as CEO since 2018. Jez’s extensive experience in the pharmaceutical industry and his leadership skills make him an invaluable asset to the organization.
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