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Insights Into the “Why” Behind Patients’ Treatment Decisions

Insights Into the “Why” Behind Patients’ Treatment Decisions

Pharmaceutical companies often put a tremendous amount of effort into connecting with prominent oncologists. These key stakeholders can indeed offer a wealth of information. Oncologists, in particular, can provide pharmaceutical companies with valuable insights into what factors guide their treatment decisions.

However, many clinicians are now withdrawing from these discussions. Heavy caseloads and tight schedules have prompted numerous oncologists to focus solely on their practice, skipping large conferences or marketing meetings. This shift can make it difficult for pharmaceutical companies to get insight into the factors that drive treatment decisions.

Yet clinicians aren’t the only decision-makers during the treatment process. Patients also play an increasingly important role. Their needs, preferences, and concerns often guide their oncologists’ decisions. Well-informed patients can help guide their clinicians toward new treatments and more comprehensive care. However, gaps in the patients’ understanding can interfere with effective cancer care.

To bridge these gaps, pharmaceutical companies must take steps to gather information about patients’ experiences during treatment. Focusing exclusively on decisions made by physicians allows valuable data to slip through the cracks. Pharmaceutical companies who dig deep into patients’ data can quickly identify the psychological factors that guide patients’ treatment decisions.

These factors are many and varied, but often include:

Likelihood of Treatment Success
Cancer patients are often anxious to achieve a “successful” treatment. However, the definition of “success” may be mutable. Even among researchers, benchmarks for success can vary. Among patients, parameters for success are often highly individualized.

Some patients plan to settle for nothing less than full remission. Others may be satisfied with adding a few more years to their lifespan. Here, too, demographics play a crucial role. Younger patients may be willing to try promising new experimental treatments, while older patients may prefer to stick with tried-and-true strategies. Extending longevity can also be a particular concern for younger patients, especially those with growing families.

Throughout the treatment process, oncologists speak with their patients about their long-term goals. Together, the doctor and patient decide on a treatment that seems likely to meet these goals. Pharmaceutical companies are wise to take these goals into account as they share information about new treatments or recent clinical trials.

Likelihood of Side Effects
Cancer treatment can save lives, but most treatments come with significant side effects. Clinicians have long been aware that different demographics tend to have varying physical responses to treatment. Psychological responses can vary, too.

Some patients may be willing to endure aggressive treatments and grueling side effects, as long as the treatment offers a chance at a cure. However, other patients may prefer treatments less likely to cause pain, fatigue, or other unpleasant side effects.

Newly diagnosed patients may not realize that cancer treatments have advanced dramatically in the last few decades. These patients may have watched a parent battle cancer 20 years ago and witnessed the harsh side effects of treatment. Pharmaceutical companies can address these fears by ensuring that patients are aware of the medical advances made in recent years.

Ability to Work or Stay Active
For many people fighting cancer, keeping active is a priority. Patients may shun treatments that could keep them off their feet for weeks or months at a time. Once again, patients may be basing their decision on outdated data or unfounded fears about cancer treatment.

As they confer with their oncologists, patients often ask whether they will be able to work while receiving care. Active athletes may also want to understand how different treatments may affect their performance. Pharmaceutical companies can play a role in these treatment decisions by understanding which demographics are most concerned about staying active. They can then reach out to oncologists who serve these populations, and provide relevant data.

Tried-and-True vs Cutting-Edge
Often, patients choosing their cancer treatment are split into 2 camps. One group may be eager to try the latest cancer treatments. These patients may see significant benefits in selecting the most advanced cancer-fighting techniques. Other patients, though, may prefer to stick with familiar treatments like chemo or surgery. These patients may fear that newer treatments haven’t been thoroughly tested or that these drugs carry certain health risks.

Pharmaceutical companies can work to address patient anxiety and to correct misinformation. Demographics play a key role in this part of the decision-making process: age, gender, race, and religious background can all affect patients’ level of trust in the medical industry. Different demographics also have varying priorities, fears, and personal beliefs.

Companies must take these factors into account and work to establish trust with prospective patients. Outreach efforts and patient-focused marketing help patients feel seen and heard. When patients believe their concerns are factored into the company’s decision-making, they are often more willing to explore new treatments.

Community Access via Scientific Engagement Strategies by Aptitude Health
CASES events bring together physicians and key thought leaders in the field of oncology or hematology. During the events, peers and experts connect, share, and discuss the latest information, and review factors that influence current treatment approaches.

The conclusions from these meeting discussions are summarized in CASES reports. Pharmaceutical companies can gain critical insights through this intelligence. With CASES, your company can better understand the factors that drive treatment decisions. You can analyze treatment patterns and gaps in patient understanding, and better comprehend the cancer care market. In addition, your company can easily spot areas where clinicians’ knowledge may be lacking, and this can guide your outreach efforts.

When physicians, patients, and pharmaceutical companies work together, everyone achieves more in the fight against cancer.

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Matthew Gordon

VP, Real-World Evidence
Matthew has more than 25 years of experience in real-world evidence and observational, non-interventional research. He has led studies across the full life cycle—from startup through publication—supporting objectives that range from understanding a disease’s natural history to fulfilling global safety surveillance requirements. Matthew brings deep expertise in orphan disease programs, having overseen more than 25 long-term, global initiatives, as well as in disease and product registries, prospective pharmacoeconomic studies, and systematic literature reviews. Matthew leads the RWE Registries team, responsible for building the business and team. Prior to joining Aptitude Health, he held senior leadership roles at Parexel, Worldwide Clinical Trials, inVentiv Health Clinical, Quintiles Outcome, and ICON Clinical Research. Matthew holds a BA in sociology from Boston University, is a long-standing member of the International Society for Pharmacoeconomics and Outcomes Research (ISPOR), and is a frequent speaker at ISPOR, the Center for Business Intelligence, and related industry conferences.

Gerald Stanvitch, PhD

VP, Scientific Content

Cate Browning, PhD

VP, Global Medical Affairs

Erin Zingales Rau

VP, Account Services

Kelly Kocor

VP, People & Culture
Kelly leads both the human resources and talent acquisition teams, ensuring that Aptitude Health attracts, retains, and develops top personnel to drive our continued success. With over 17 years of experience transforming global HR initiatives, Kelly is an expert in harmonizing HR policies and fostering a culture of engagement and partnership. She is committed to partnering with all areas of the business to ensure full regulatory compliance and delivering value-added services to our organization and its people. Kelly is passionate about developing and implementing HR strategies that help support our employees’ professional and personal growth. She is dedicated to fostering a culture that encourages innovation, collaboration, and inclusivity, helping Aptitude Health continue to be a great place to work.

Bart Zygmond

VP, Finance
Bart brings a wealth of experience to the organization, having worked in the life sciences, pharmaceuticals, manufacturing, and service industries. With his expertise in financial reporting, US GAAP, SOX, cash flow modeling, and financial analysis, he plays a crucial role in the company’s financial management and strategy. Prior to joining Aptitude Health as VP, Finance, Bart held several controller positions: at Q2 Solutions, he oversaw the global finance team and financial operations, ensuring the accurate and timely financial reporting of the company. He also held controller positions at Domtar Inc and Veristat.

Eugene Vissers, MD

Senior VP, Global Scientific Content
Eugene is a seasoned medical doctor with over 20 years of international experience in pharma, consultancy, and agency environments. Eugene leads the US team of dedicated experts responsible for developing high-quality medical content. Prior to joining Aptitude Health, Eugene served as medical director at Ipsen and AstraZeneca. With both his medical degree and an MBA, Eugene brings a unique perspective to his role. His clinical background, combined with his business acumen, allows him to develop innovative strategies that drive results. Under Eugene’s leadership, the medical content team delivers scientific information of the highest quality, providing valuable insights to our clients around the world.

Adrian Barfield

VP, US Business Development

Kelley Hernandez

Executive VP, US Business Development
Kelley has over 18 years of experience in the oncology space. Kelley joined Aptitude Health after working with Cardinal Health, where she was part of the Healthcare and Analytics Division, and finished her tenure there with VitalSource™ (GPO division). As the leader of the strategic business development team for the US, Kelley brings a wealth of expertise to the organization. Her experience in the healthcare industry, combined with her ability to identify and capitalize on new business opportunities, is invaluable in driving the company’s growth and success. Kelley’s dedication to building strong relationships with life science partners is a testament to her commitment to delivering exceptional value to the healthcare industry.

Adam Sinensky, MBA

Chief Technology Officer

Adam has over 20 years of experience in the healthcare industry and an MBA in healthcare management. After 10 years as a strategy consultant to life science companies, Adam has spent the last decade as a product and strategy leader focused on bringing technology products to market across the payor, provider, and life sciences segments. By combining his business acumen and experience working directly with software developers, engineers, and data scientists, Adam has successfully led numerous product launches and enhancements from ideation to development and go-to-market initiatives. His product and change management expertise has led organizational shifts from services to technology at companies such as Change Healthcare and Datavant/Ciox. At Aptitude Health, Adam is responsible for growing our portfolio of product offerings by leveraging real-world data and artificial intelligence with our existing solutions and industry-leading Axess Network of healthcare providers. He also oversees our IT and cybersecurity teams.

Stefanie Daniels

Chief Commercial Officer

Stefanie is a seasoned healthcare executive with over 20 years of experience in oncology. She brings a wealth of knowledge and expertise to the organization. Stefanie joined Aptitude Health after spending over a decade as a senior director at Physicians’ Education Resource, an oncology CME vendor. During her tenure, she led and managed teams responsible for grant development/acquisition, program creation/execution, and faculty management. Stefanie’s deep understanding of the oncology industry and her ability to lead teams through complex projects make her a vital part of the organization’s success. Her dedication to providing high-quality solutions to our life science partners is a testament to her commitment to improving cancer patient care.

Jason Cash

Chief Financial Officer

Jason is an accomplished finance professional with over 20 years of experience in the pharmaceutical services industry. Throughout his career, he has demonstrated a keen ability to navigate high-growth organizations, delivering exceptional results. Before joining Aptitude Health, Jason served as the CFO of Veristat International, a global contract research organization. In this role, he led the financial strategy and played a pivotal role in driving the company’s growth and success. Jason’s wealth of experience and expertise in financial management make him an essential member of the leadership team. His strategic thinking and ability to drive results are highly respected within the industry.

Jez Moulding

Chief Executive Officer
Jez is a seasoned leader with over 20 years of experience in general management and regional president roles. He has a proven track record of success in the healthcare industry, having worked in the US, Japan, Australia, Korea, South Africa, France, and the UK for Sanofi, where he supported the launch of 10 new drugs across various therapeutic areas. As chief commercial officer at UDG Healthcare and EVP at Ashfield, Jez demonstrated his expertise in developing and implementing successful business strategies. He joined Aptitude Health from Pharmaspectra, an IQVIA business, where he served as CEO since 2018. Jez’s extensive experience in the pharmaceutical industry and his leadership skills make him an invaluable asset to the organization.