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Decision Support Tools for Surgical Referrals Improve Outcomes

Objective data are routinely used by physicians when making recommendations for prescription medications, but when making surgical referrals, the decision process is less well defined. Since differences in hospital quality and performance have been shown to affect surgical outcomes, two recent JAMA articles focused on decision rationale and whether outcomes may be improved with evidence-based decision support for surgical referrals.

In one study, Dr Naik, et al conducted a qualitative analysis of primary care physician (PCP) responses at Penn Medicine (Pennsylvania, United States) to assess how decision-making differs for medication recommendations vs referrals to specific surgeons or hospitals. This study found that PCPs used decision support tools with consideration of patient attributes when making prescription medication recommendations, but relied on professional experiences, subjective information on quality, and convenience (eg, location, in-network advantages) when making surgical referrals. The authors suggest that supporting referral decision-making with valid and reliable data on surgeon and hospital quality may reduce variability and improve surgical outcomes.

Furthermore, in an analysis of patients with colorectal cancer by Dr Finn, et al, data-driven hospital selection for patients with colorectal cancer (n=21,098) in Florida, United States was shown to affect outcomes. The primary outcome was mean change in social welfare, which provides an economic assessment by balancing the simulated mortality benefit associated with data-driven hospital selection with costs of care at alternative hospitals. They found that use of procedure-specific hospital performance in hospital selection was associated with improved outcomes overall. Patient social welfare increased by nearly $2,000 and was associated with decreased in-hospital mortality risk. Estimated costs of care increased but were offset by the value of additional life gained due to avoidance of in-hospital mortality. Black patients experienced higher gains in mean social welfare than White patients and a greater decrease in mortality risk by selecting the highest-performing hospital. The authors estimated a societal savings of approximately $9,765,000 if data-driven hospital selection were implemented for a population of 5,000 surgical patients with colorectal cancer. The study supports use of outcomes data by patients and referring physicians to make informed decisions when selecting a hospital and could be used to transform care and guide policy in cancer surgery.

High level
Referring physicians typically rely on subjective evaluations of clinical skill, reputation, and convenience, rather than using volume or outcomes data to guide their recommendations. Dr Naik, et al suggest that the practice of using decision support tools for medication selection is transferrable to the surgical referral process and, and ultimately may improve surgical outcomes by encouraging physicians to refer to objectively higher-quality surgeons or hospitals. Similarly, Dr Finn, et al, suggested that surgical outcomes data can be used to guide policy in cancer care (including surgical referral guidance) for improved outcomes and reduced disparities. Providing regular updates on hospital outcomes data can help physicians optimize referrals. Likewise, availability of publicly reported information on surgical outcomes data and hospital performance for individual procedures may help patients weigh their potential outcomes against other considerations to make the optimal choice when selecting a hospital for their procedure.

Ground level
Interventions to promote selection of higher-quality hospitals for surgical referrals may help to improve outcomes and reduce both disparities and costs. Outcomes data provide a reliable evidence base for decision support tools. Considering publicly reported information on surgical outcomes data and hospital performance for individual procedures may help clinicians and patients weigh their potential outcomes to make the optimal choice when selecting a hospital for their procedure.

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Matthew Gordon

VP, Real-World Evidence
Matthew has more than 25 years of experience in real-world evidence and observational, non-interventional research. He has led studies across the full life cycle—from startup through publication—supporting objectives that range from understanding a disease’s natural history to fulfilling global safety surveillance requirements. Matthew brings deep expertise in orphan disease programs, having overseen more than 25 long-term, global initiatives, as well as in disease and product registries, prospective pharmacoeconomic studies, and systematic literature reviews. Matthew leads the RWE Registries team, responsible for building the business and team. Prior to joining Aptitude Health, he held senior leadership roles at Parexel, Worldwide Clinical Trials, inVentiv Health Clinical, Quintiles Outcome, and ICON Clinical Research. Matthew holds a BA in sociology from Boston University, is a long-standing member of the International Society for Pharmacoeconomics and Outcomes Research (ISPOR), and is a frequent speaker at ISPOR, the Center for Business Intelligence, and related industry conferences.

Gerald Stanvitch, PhD

VP, Scientific Content

Cate Browning, PhD

VP, Global Medical Affairs

Erin Zingales Rau

VP, Account Services

Kelly Kocor

VP, People & Culture
Kelly leads both the human resources and talent acquisition teams, ensuring that Aptitude Health attracts, retains, and develops top personnel to drive our continued success. With over 17 years of experience transforming global HR initiatives, Kelly is an expert in harmonizing HR policies and fostering a culture of engagement and partnership. She is committed to partnering with all areas of the business to ensure full regulatory compliance and delivering value-added services to our organization and its people. Kelly is passionate about developing and implementing HR strategies that help support our employees’ professional and personal growth. She is dedicated to fostering a culture that encourages innovation, collaboration, and inclusivity, helping Aptitude Health continue to be a great place to work.

Bart Zygmond

VP, Finance
Bart brings a wealth of experience to the organization, having worked in the life sciences, pharmaceuticals, manufacturing, and service industries. With his expertise in financial reporting, US GAAP, SOX, cash flow modeling, and financial analysis, he plays a crucial role in the company’s financial management and strategy. Prior to joining Aptitude Health as VP, Finance, Bart held several controller positions: at Q2 Solutions, he oversaw the global finance team and financial operations, ensuring the accurate and timely financial reporting of the company. He also held controller positions at Domtar Inc and Veristat.

Eugene Vissers, MD

Senior VP, Global Scientific Content
Eugene is a seasoned medical doctor with over 20 years of international experience in pharma, consultancy, and agency environments. Eugene leads the US team of dedicated experts responsible for developing high-quality medical content. Prior to joining Aptitude Health, Eugene served as medical director at Ipsen and AstraZeneca. With both his medical degree and an MBA, Eugene brings a unique perspective to his role. His clinical background, combined with his business acumen, allows him to develop innovative strategies that drive results. Under Eugene’s leadership, the medical content team delivers scientific information of the highest quality, providing valuable insights to our clients around the world.

Adrian Barfield

VP, US Business Development

Kelley Hernandez

Executive VP, US Business Development
Kelley has over 18 years of experience in the oncology space. Kelley joined Aptitude Health after working with Cardinal Health, where she was part of the Healthcare and Analytics Division, and finished her tenure there with VitalSource™ (GPO division). As the leader of the strategic business development team for the US, Kelley brings a wealth of expertise to the organization. Her experience in the healthcare industry, combined with her ability to identify and capitalize on new business opportunities, is invaluable in driving the company’s growth and success. Kelley’s dedication to building strong relationships with life science partners is a testament to her commitment to delivering exceptional value to the healthcare industry.

Adam Sinensky, MBA

Chief Technology Officer

Adam has over 20 years of experience in the healthcare industry and an MBA in healthcare management. After 10 years as a strategy consultant to life science companies, Adam has spent the last decade as a product and strategy leader focused on bringing technology products to market across the payor, provider, and life sciences segments. By combining his business acumen and experience working directly with software developers, engineers, and data scientists, Adam has successfully led numerous product launches and enhancements from ideation to development and go-to-market initiatives. His product and change management expertise has led organizational shifts from services to technology at companies such as Change Healthcare and Datavant/Ciox. At Aptitude Health, Adam is responsible for growing our portfolio of product offerings by leveraging real-world data and artificial intelligence with our existing solutions and industry-leading Axess Network of healthcare providers. He also oversees our IT and cybersecurity teams.

Stefanie Daniels

Chief Commercial Officer

Stefanie is a seasoned healthcare executive with over 20 years of experience in oncology. She brings a wealth of knowledge and expertise to the organization. Stefanie joined Aptitude Health after spending over a decade as a senior director at Physicians’ Education Resource, an oncology CME vendor. During her tenure, she led and managed teams responsible for grant development/acquisition, program creation/execution, and faculty management. Stefanie’s deep understanding of the oncology industry and her ability to lead teams through complex projects make her a vital part of the organization’s success. Her dedication to providing high-quality solutions to our life science partners is a testament to her commitment to improving cancer patient care.

Jason Cash

Chief Financial Officer

Jason is an accomplished finance professional with over 20 years of experience in the pharmaceutical services industry. Throughout his career, he has demonstrated a keen ability to navigate high-growth organizations, delivering exceptional results. Before joining Aptitude Health, Jason served as the CFO of Veristat International, a global contract research organization. In this role, he led the financial strategy and played a pivotal role in driving the company’s growth and success. Jason’s wealth of experience and expertise in financial management make him an essential member of the leadership team. His strategic thinking and ability to drive results are highly respected within the industry.

Jez Moulding

Chief Executive Officer
Jez is a seasoned leader with over 20 years of experience in general management and regional president roles. He has a proven track record of success in the healthcare industry, having worked in the US, Japan, Australia, Korea, South Africa, France, and the UK for Sanofi, where he supported the launch of 10 new drugs across various therapeutic areas. As chief commercial officer at UDG Healthcare and EVP at Ashfield, Jez demonstrated his expertise in developing and implementing successful business strategies. He joined Aptitude Health from Pharmaspectra, an IQVIA business, where he served as CEO since 2018. Jez’s extensive experience in the pharmaceutical industry and his leadership skills make him an invaluable asset to the organization.
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